(r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4 -yl]propionic Acid Sesquihydrate

  • Catalogue No.: IM007508
  • CAS No.: 209977-56-0
  • Mol. Formula: C₉H₁₂N₂O₆•1.5H₂O
SKU: IM007508 카테고리: , ,

설명

Catalogue Number IM007508
CAS No. 209977-56-0
Chemical Name (r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4 -yl]propionic Acid Sesquihydrate
Synonyms AMOA; α-Amino-3-(carboxymethoxy)-5-methyl-4-isoxazolepropanoic Acid Hydrate (2:3)
Molecular Formula C₉H₁₂N₂O₆•1.5H₂O
Molecular Weight 271.23
Appearance White Crystalline Solid
Melting Point 230°C dec.
Storage -20°C, Hygroscopic
Solubility Hot Methanol, Water
Stability Store in freezer at -20°C
Applications A selective inhibitor of [3H]-AMPA binding in rat brain membranes. AMOA shows little affinity for [3H]-kainate binding sites or other sites on the NMDA receptor-channel complex, as represented by binding of [3H]-CPP, [3H]-gly or [3H]-MK-801. AMOA also selectively antagonizes AMPA-induced responses in rat cortical wedge preparations relative to kainate-, quisqualate- and NMDA-induced responses.
Category Standards; Amino Acids; Neurochemicals;

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