11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

Catalogue No.: IM049058
CAS No.: 133627-24-4
Mol. Formula: C₁₅H₁₄N₄O₂

11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one

Description

Catalogue Number	IM049058
CAS No.	133627-24-4
Chemical Name	11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
Synonyms	12-Hydroxy Nevirapine;
Molecular Formula	C₁₅H₁₄N₄O₂
Molecular Weight	282.3
Appearance	Pale Yellow to Light Brown Solid
Melting Point	>184ºC (dec.)
Storage	4°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Applications	11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, is a metabolite of Nevirapine (N391275), which is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. It is also an antiviral.
Category	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Benzodiazepines;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.

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