(11b,16a)-21-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-11,16,17-trihydroxy-pregna-1,4-diene-3,20-dione

Catalogue No.: IM068337
CAS No.: 1221150-20-4
Mol. Formula: C₂₇H₄₂O₆Si

Description

Catalogue Number	IM068337
CAS No.	1221150-20-4
Chemical Name	(11b,16a)-21-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-11,16,17-trihydroxy-pregna-1,4-diene-3,20-dione
Synonyms	(8S,9S,10R,11S,13S,14S,16R,17S)-17-(2-((tert-Butyldimethylsilyl)oxy)acetyl)-11,16,17-trihydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Molecular Formula	C₂₇H₄₂O₆Si
Molecular Weight	490.7
Appearance	White Solid
Solubility	Dichloromethane, Ethyl Acetate
Applications	(11b,16a)-21-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-11,16,17-trihydroxy-pregna-1,4-diene-3,20-dione is an intermediate in the synthesis of 16a-Butyloxyprednisolone (B693880). 16a-Butyloxyprednisolone (Budesonide EP Impurity I) is an impurity of Budesonide (B689460), a non-halogenated glucocorticoid intended for the local treatment of lung disease.
Category	Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;

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