(3a)-Allopregnanolone

  • Catalogue No.: IM005679
  • CAS No.: 516-54-1
  • Mol. Formula: C₂₁H₃₄O₂

Description

Catalogue Number IM005679
CAS No. 516-54-1
Chemical Name (3a)-Allopregnanolone
Synonyms (+)-3?-Hydroxy-5?-pregnan-20-one; (3?,5?)-3-Hydroxypregnan-20-one; 3?,5?-THP; 3?,5?-Tetrahydroprogesterone; 3?-Hydroxy-5?-dihydroprogesterone; 3?-Hydroxy-5?-pregnan-20-one; 3?-Hydroxy-5?-pregnane-20-one; 5?-Pregnan-3?-ol-20-one; 5?-Pregnane-3?-ol-20-one; Allopregnan-3?-ol-20-one; Allopregnanolone; Allotetrahydroprogesterone;
Molecular Formula C₂₁H₃₄O₂
Molecular Weight 318.49
Appearance White to Off-White Solid
Melting Point 174-175C
Storage 4°C
Solubility Chloroform (Slightly), Methanol (Slightly)
Applications (3?)-Allopregnanolone acts as a GABAA receptor positive allosteric modulator. (3?)-Allopregnanolone is a metabolite of Progesterone (P755900). (3?)-Allopregnanolone is a neuroactive steroid present in the blood and also the brain. In 2019, the US Food and Drug Administration approved (3?)-Allopregnanolone as an intravenous infusion for treating postpartum depression.
Category Standards; Steroids; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.

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