Description
Catalogue Number | IM040483 |
CAS No. | 137982-91-3 |
Chemical Name | 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one |
Synonyms | 1-(2-Methyl-4-nitrobenzoyl)-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one; 7-Chloro-1-(2-methyl-4-nitrobenzoyl)-5-oxo-2,3,4,5+tetrahydro-1H-1-benzazepine; |
Molecular Formula | C₁₈H₁₅ClN₂O₄ |
Molecular Weight | 358.78 |
Appearance | White to Off-White Solid |
Melting Point | 152 – 155°C |
Storage | 4°C, Inert atmosphere |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Applications | 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one is an intermediate in synthesizing Tolvaptan-d7 (T536652), a labelled Tolvaptan (T536650). It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH). |
Category | Standards; Benzodiazepines; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
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