7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one

  • Catalogue No.: IM040483
  • CAS No.: 137982-91-3
  • Mol. Formula: C₁₈H₁₅ClN₂O₄
SKU: IM040483 Categories: ,

Description

Catalogue Number IM040483
CAS No. 137982-91-3
Chemical Name 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one
Synonyms 1-(2-Methyl-4-nitrobenzoyl)-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one; 7-Chloro-1-(2-methyl-4-nitrobenzoyl)-5-oxo-2,3,4,5+tetrahydro-1H-1-benzazepine;
Molecular Formula C₁₈H₁₅ClN₂O₄
Molecular Weight 358.78
Appearance White to Off-White Solid
Melting Point 152 – 155°C
Storage 4°C, Inert atmosphere
Solubility DMSO (Slightly), Methanol (Slightly)
Applications 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one is an intermediate in synthesizing Tolvaptan-d7 (T536652), a labelled Tolvaptan (T536650). It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
Category Standards; Benzodiazepines;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.

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