Description
Catalogue Number | IM004073 |
CAS No. | 13434-13-4 |
Chemical Name | (-)-Actinonin |
Synonyms | (2R)-N4-Hydroxy-N1-[(1S)-1-[[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]carbonyl]-2-methylpropyl]-2-pentyl-butanediamide; Actinonine; 3-[[1-[[2-(Hydroxymethyl)-1-pyrrolidinyl]carbonyl]-2-methylpropyl]carbamoyl]octanohydroxamic Acid; Actinonin; CONA 57; Ro 06-1467; |
Molecular Formula | C₁₉H₃₅N₃O₅ |
Molecular Weight | 385.5 |
Appearance | White to Light Beige Solid |
Melting Point | 137-139°C |
Storage | -20°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Applications | (-)-Actinonin is a bioactive peptide and antibiotic that is a potent inhibitor of aminopeptidase M and leucine aminopeptidase. Actinonin has observed to be an inhibitor of peptide deformylase, meprin A, and thermolysin. Actinonin also inhibits tumor cell invasion and matrix degradation along with displayed antitumor activity in vitro and in vivo as well as acting as an apoptotic inducer. |
Category | Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
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