(-)-Actinonin

  • Catalogue No.: IM004073
  • CAS No.: 13434-13-4
  • Mol. Formula: C₁₉H₃₅N₃O₅

Description

Catalogue Number IM004073
CAS No. 13434-13-4
Chemical Name (-)-Actinonin
Synonyms (2R)-N4-Hydroxy-N1-[(1S)-1-[[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]carbonyl]-2-methylpropyl]-2-pentyl-butanediamide; Actinonine; 3-[[1-[[2-(Hydroxymethyl)-1-pyrrolidinyl]carbonyl]-2-methylpropyl]carbamoyl]octanohydroxamic Acid; Actinonin; CONA 57; Ro 06-1467;
Molecular Formula C₁₉H₃₅N₃O₅
Molecular Weight 385.5
Appearance White to Light Beige Solid
Melting Point 137-139°C
Storage -20°C
Solubility DMSO (Slightly), Methanol (Slightly)
Applications (-)-Actinonin is a bioactive peptide and antibiotic that is a potent inhibitor of aminopeptidase M and leucine aminopeptidase. Actinonin has observed to be an inhibitor of peptide deformylase, meprin A, and thermolysin. Actinonin also inhibits tumor cell invasion and matrix degradation along with displayed antitumor activity in vitro and in vivo as well as acting as an apoptotic inducer.
Category Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.

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