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Description
| Catalogue Number | IM003083 |
| CAS No. | — |
| Chemical Name | Allyloxy-3-oxo-2-((4-oxopentan-2-yl)amino)propyl)thio Cilastatin Derivative |
| Synonyms | Allyl (Z)-7-(((2S)-3-(Allyloxy)-3-oxo-2-((4-oxopentan-2-yl)amino)propyl)thio)-2-((R)-2,2-dimethylcyclopropane-1-carboxamido)hept-2-enoate; |
| Molecular Formula | C₂₇H₄₂N₂O₆S |
| Molecular Weight | 552.7 |
| Applications | Allyloxy-3-oxo-2-((4-oxopentan-2-yl)amino)propyl)thio Cilastatin derivative is an intermediate in the synthesis of (Z)-7-(((2R)-2-Carboxy-2-((4-oxopentan-2-yl)amino)ethyl)thio)-2-((S)-2,2-dimethylcyclopropanecarboxamido)hept-2-enoic Acid (C178930), an impurity of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct. |
| Category | Building Blocks; Miscellaneous; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
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