(-)-Ascofuranone

  • Catalogue No.: IM013278
  • CAS No.: 38462-04-3
  • Mol. Formula: C₂₃H₂₉ClO₅

Description

Catalogue Number IM013278
CAS No. 38462-04-3
Chemical Name (-)-Ascofuranone
Synonyms 3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,6E)-3-methyl-7-[(2S)-tetrahydro-5,5-dimethyl-4-oxo-2-furanyl]-2,6-octadien-1-yl]benzaldehyde;[S-(E,E)]-3-Chloro-4,6-dihydroxy-2-methyl-5-[3-methyl-7-(tetrahydro-5,5-dimethyl-4-oxo-2-furanyl)-2,6-octadienyl]-benzaldehyde; Ascofuranone;
Molecular Formula C₂₃H₂₉ClO₅
Molecular Weight 420.93
Applications (-)-Ascofuranone is an antibiotic with antitumor activity. It suppresses PMA-mediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanisms. (-)-Ascofuranone was effective in the treatment against Trypanosoma brucei brucei infection in mice.
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.

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