Controlled Substance

Catalogue No.: IM100673
CAS No.: 918504-65-1
Mol. Formula: C23H18ClF2N3O3S

Description

Catalogue Number	IM100673
CAS No.	918504-65-1
Chemical Name	Vemurafenib (10mM in DMSO)
Synonyms	N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide; PLX 4032; RG 7204; Ro 51-85426;
Molecular Formula	C23H18ClF2N3O3S
Molecular Weight	489.92
Applications	Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. Potent B-Raf inhibitor
Category	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Solutions; Kits;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.