Panobinostat-d8 (Major) Hydrochloride Salt

Catalogue No.: IM124635
CAS No.: &#8212;
Mol. Formula: C₂₁H₁₆D₈ClN₃O₂

Description

Catalogue Number	IM124635
CAS No.	—
Alternate CAS No.	E/Z Mixture: 1185237-51-7;unlabelled: 404950-80-7
Chemical Name	Panobinostat-d8 (Major) Hydrochloride Salt
Synonyms	(2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl-d8)ethyl]amino]methyl]phenyl]-2-propenamide Hydrochloride; LBH 589-d8 Hydrochloride;
Molecular Formula	C₂₁H₁₆D₈ClN₃O₂
Molecular Weight	393.94
Appearance	Tan to Light Beige Solid
Melting Point	>143°C (dec.)
Storage	-20°C, Inert atmosphere
Solubility	DMSO (Slightly), Methanol (Slightly)
Applications	The novel labelled histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells.
Category	Research Tools; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Tryptamines;

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