Description
Catalogue Number | IM124634 |
CAS No. | 404950-80-7 |
Chemical Name | Panobinostat(LBH-589) |
Synonyms | (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide; LBH 589; LBH-589 |
Molecular Formula | C₂₁H₂₃N₃O₂ |
Molecular Weight | 349.43 |
Appearance | White to Yellow Solid |
Melting Point | >115°C (dec.) |
Storage | -20°C, Hygroscopic |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Stability | Hygroscopic |
Applications | The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells. Potent Histone deacetylase inhibitor. |
Category | Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Tryptamines; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.