Panobinostat(LBH-589)

  • Catalogue No.: IM124634
  • CAS No.: 404950-80-7
  • Mol. Formula: C₂₁H₂₃N₃O₂

Description

Catalogue Number IM124634
CAS No. 404950-80-7
Chemical Name Panobinostat(LBH-589)
Synonyms (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide; LBH 589; LBH-589
Molecular Formula C₂₁H₂₃N₃O₂
Molecular Weight 349.43
Appearance White to Yellow Solid
Melting Point >115°C (dec.)
Storage -20°C, Hygroscopic
Solubility DMSO (Slightly), Methanol (Slightly)
Stability Hygroscopic
Applications The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells. Potent Histone deacetylase inhibitor.
Category Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Tryptamines;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.