(R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
- Catalogue No.: IM015309
- CAS No.: 180637-89-2
- Mol. Formula: C₂₂H₂₄N₂O₂S
Description
| Catalogue Number | IM015309 |
| CAS No. | 180637-89-2 |
| Chemical Name | (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole |
| Synonyms | 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole; (R)-3-[(1-Methyl-2-pyrrolidinyl)methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole |
| Molecular Formula | C₂₂H₂₄N₂O₂S |
| Molecular Weight | 380.5 |
| Solubility | Dichloromethane, Dimethylformamide, Methanol |
| Applications | (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole is the free base of (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole Hydrobromide (B120725), which is an impurity of Eletriptan (E505000). Eletriptan is a selective serotonin 5-HT1B and 5-HT1D receptor agonist and used to treat migraines (1,2,3). (R)-5-(2-Benzenesulphonylethenyl)-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole is also an intermediate in the synthesis of 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-1-[1-[3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indol-5-yl]-2-(phenylsulfonyl)ethyl]-5-[(1E)-2-(phenylsulfonyl)ethenyl]-1H-indole (M320195). |
| Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Tryptamines; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
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