Romidepsin

Catalogue No.: IM133046
CAS No.: 128517-07-7
Mol. Formula: C₂₄H₃₆N₄O₆S₂

Description

Catalogue Number	IM133046
CAS No.	128517-07-7
Chemical Name	Romidepsin
Synonyms	Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl] Cyclic (35)-Disulfide; [S-(E)]-N-(3-Hydroxy-7-mercapto-1-oxo-4-
Molecular Formula	C₂₄H₃₆N₄O₆S₂
Molecular Weight	540.7
Appearance	White to Off-White Solid
Melting Point	219-224°C
Storage	-20°C, Inert atmosphere, Light sensitive
Solubility	Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated)
Stability	Light Sensitive
Applications	Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xenograft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor.
Category	Standards; Enzyme Activators and Inhibitors; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.