(r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4 -yl]propionic Acid Sesquihydrate

Catalogue No.: IM007508
CAS No.: 209977-56-0
Mol. Formula: C₉H₁₂N₂O₆•1.5H₂O

SKU: IM007508 Categories: Amino Acids, Neurochemicals, Standards

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Description

Catalogue Number	IM007508
CAS No.	209977-56-0
Chemical Name	(r,s)-2-Amino-3-[3-(carboxymethoxy)-5-methyl-isoxazol-4 -yl]propionic Acid Sesquihydrate
Synonyms	AMOA; α-Amino-3-(carboxymethoxy)-5-methyl-4-isoxazolepropanoic Acid Hydrate (2:3)
Molecular Formula	C₉H₁₂N₂O₆•1.5H₂O
Molecular Weight	271.23
Appearance	White Crystalline Solid
Melting Point	230°C dec.
Storage	-20°C, Hygroscopic
Solubility	Hot Methanol, Water
Stability	Store in freezer at -20°C
Applications	A selective inhibitor of [3H]-AMPA binding in rat brain membranes. AMOA shows little affinity for [3H]-kainate binding sites or other sites on the NMDA receptor-channel complex, as represented by binding of [3H]-CPP, [3H]-gly or [3H]-MK-801. AMOA also selectively antagonizes AMPA-induced responses in rat cortical wedge preparations relative to kainate-, quisqualate- and NMDA-induced responses.
Category	Standards; Amino Acids; Neurochemicals;

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