Sofosbuvir α-Isomer
- Catalogue No.: IM135365
- CAS No.: —
- Mol. Formula: C₂₂H₂₉FN₃O₉P
Description
| Catalogue Number | IM135365 |
| CAS No. | — |
| Chemical Name | Sofosbuvir α-Isomer |
| Synonyms | (S)-Isopropyl 2-(((S)-(((2R,3R,4R,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate |
| Molecular Formula | C₂₂H₂₉FN₃O₉P |
| Molecular Weight | 529.45 |
| Applications | Sofosbuvir α-Isomer is a derivative compound of Sofosbuvir (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. |
| Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
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