Description
Catalogue Number | IM034054 |
CAS No. | 1936429-06-9 |
Chemical Name | tert-Butyl 3-Bromo-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate |
Synonyms | 1,1-Dimethylethyl 3-Bromo-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate |
Molecular Formula | C₁₁H₁₆BrN₃O₂ |
Molecular Weight | 302.17 |
Appearance | Light Green Solid |
Solubility | Dichloromethane |
Applications | tert-Butyl 3-Bromo-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology. |
Category | Building Blocks; Miscellaneous; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
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