tert-Butyl 3-Bromo-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate

  • Catalogue No.: IM034054
  • CAS No.: 1936429-06-9
  • Mol. Formula: C₁₁H₁₆BrN₃O₂
SKU: IM034054 Categories: ,

Description

Catalogue Number IM034054
CAS No. 1936429-06-9
Chemical Name tert-Butyl 3-Bromo-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
Synonyms 1,1-Dimethylethyl 3-Bromo-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate
Molecular Formula C₁₁H₁₆BrN₃O₂
Molecular Weight 302.17
Appearance Light Green Solid
Solubility Dichloromethane
Applications tert-Butyl 3-Bromo-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.
Category Building Blocks; Miscellaneous;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.

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