1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE)

  • Catalogue No.: IM068482
  • CAS No.: 4004-05-1
  • Mol. Formula: C₄₁H₇₈NO₈P
SKU: IM068482 카테고리: , ,

설명

Catalogue Number IM068482
CAS No. 4004-05-1
Chemical Name 1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE)
Synonyms 9-Octadecenoic acid (9Z)-1,1'-[(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester;9-Octadecenoic acid (9Z)-(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester; (R)-9-Octadecenoic acid (Z)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester; L-Olein 1,2-di-2-Aminoethyl Hydrogen Phosphate; L-2-Amino-ethanol Dihydrogen Phosphate Monoester with 1,2-Diolein; 1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphorylethanolamine; Coatsome MC 8181; Coatsome ME 8181; DOPE; Dioleoyl-L-α-phosphatidylethanolamine; Dioleoylphosphatidylethanolamine; L-α-Dioleoylphosphatidylethanolamine
Molecular Formula C₄₁H₇₈NO₈P
Molecular Weight 744.03
Appearance White to Off-White Solid
Melting Point >170˚C (dec.)
Storage -20°C, Inert atmosphere
Solubility Chloroform (Slightly), Methanol (Slightly)
Applications 1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.
Category Research Tools; Molecular Biology; Amino Acids/Peptides;

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