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| Catalogue Number | IM013278 |
| CAS No. | 38462-04-3 |
| Chemical Name | (-)-Ascofuranone |
| Synonyms | 3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,6E)-3-methyl-7-[(2S)-tetrahydro-5,5-dimethyl-4-oxo-2-furanyl]-2,6-octadien-1-yl]benzaldehyde;[S-(E,E)]-3-Chloro-4,6-dihydroxy-2-methyl-5-[3-methyl-7-(tetrahydro-5,5-dimethyl-4-oxo-2-furanyl)-2,6-octadienyl]-benzaldehyde; Ascofuranone; |
| Molecular Formula | C₂₃H₂₉ClO₅ |
| Molecular Weight | 420.93 |
| Applications | (-)-Ascofuranone is an antibiotic with antitumor activity. It suppresses PMA-mediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanisms. (-)-Ascofuranone was effective in the treatment against Trypanosoma brucei brucei infection in mice. |
| Category | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
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