설명
Catalogue Number | IM036031 |
CAS No. | 5096-57-1 |
Chemical Name | (S)-(-)-Canadine |
Synonyms | (S)-5,8,13,13a-tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine; Canadine; (-)-Canadine; (-)-Tetrahydroberberine; (-)-α-Canadine; (S)-(-)-7,8,13,13a-Tetrahydroberberine; (S)-(-)-Tetrahydroberberine; (S)-Canadine; (S)-Tetrahydroberberine; 9,10-Dimethoxy-2,3-(methylenedioxy)-13aα-berbine; l-Canadine; α-Canadine |
Molecular Formula | C₂₀H₂₁NO₄ |
Molecular Weight | 339.39 |
Appearance | Pale Yellow to Light Yellow Solid |
Melting Point | 132-134°C |
Storage | 4°C |
Solubility | Chloroform, Ethyl Acetate (Slightly), Methanol (Very Slightly, Heated) |
Applications | (S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as new antipsychotic agents. |
Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
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