(S)-(-)-Canadine

  • Catalogue No.: IM036031
  • CAS No.: 5096-57-1
  • Mol. Formula: C₂₀H₂₁NO₄

설명

Catalogue Number IM036031
CAS No. 5096-57-1
Chemical Name (S)-(-)-Canadine
Synonyms (S)-5,8,13,13a-tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine; Canadine; (-)-Canadine; (-)-Tetrahydroberberine; (-)-α-Canadine; (S)-(-)-7,8,13,13a-Tetrahydroberberine; (S)-(-)-Tetrahydroberberine; (S)-Canadine; (S)-Tetrahydroberberine; 9,10-Dimethoxy-2,3-(methylenedioxy)-13aα-berbine; l-Canadine; α-Canadine
Molecular Formula C₂₀H₂₁NO₄
Molecular Weight 339.39
Appearance Pale Yellow to Light Yellow Solid
Melting Point 132-134°C
Storage 4°C
Solubility Chloroform, Ethyl Acetate (Slightly), Methanol (Very Slightly, Heated)
Applications (S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as new antipsychotic agents.
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.

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