trans-Ned-19

Catalogue No.: IM118955
CAS No.: 1354235-96-3
Mol. Formula: C₃₀H₃₁FN₄O₃

설명

Catalogue Number	IM118955
CAS No.	1354235-96-3
Alternate CAS No.	1137263-70-7 (for relative stereochem)
Chemical Name	trans-Ned-19
Synonyms	(1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;
Molecular Formula	C₃₀H₃₁FN₄O₃
Molecular Weight	514.59
Appearance	Yellow Solid
Melting Point	168-173°C
Storage	4°C
Solubility	Methanol
Applications	trans-Ned-19 is a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells.
Category	Standards; Enzyme Activators and Inhibitors; Fluorescent Reagents; Pharmaceutical/API Drug Impurities/Metabolites;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.